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Veterinary
API's

Coccidostats

Coccidostats are agents that are used to prevent coccidiosis in animals. Amprolium is a coccidiostat used in poultry. It is a particularly effective anticocciosis in conjunction with sulfonamides fort he treatment and prevention of coccidiosis in broilers as well as laying hens.

Amprolium HCL

  • Appearance: Clean, white to yellow powder
  • Identification IR: Passes test (USP, BP)
  • Identification UV: - Absorptivities at 246 nm (calculated on dried basis) do not differ by more than 3.0 (USP) - At 246 nm absorbance about 0.84 and at 262 nm absorbance about 0.80 (BP)
  • Identification Chlorides: Passes test (BP)
  • Identification Naphtalene diol: Deep violet colour / passes test (BP)
  • Thin layer chromatography: Passes test
  • Assay – HPLC (dry basis): 97.5 – 101.0 % (USP)
  • Assay – Titration (dry basis): 97.5 – 101.0 % (BP)
  • Impurities: a-Picoline: Absorbance at 262 nm ≤ 0.52 (BP)
  • Total volatile alkalies: Max. 1.0 %
  • Loss on drying: Max. 1.0 % (USP, BP)
  • Surface active agent: Max. 0.025 %
  • Residue on ignition/Sulphated ash: Max. 0.1 % (BP)
  • Microscopic examination: Passes test
  • Absence of extraneous matter: Passes test
  • Solubitity: Freely soluble in water
  • Organic volatile impurity-GC: - o-Xylene: Max. 50 ppm - m-Xylene: Max. 50 ppm - p-Xylene: Max 50 ppm - Isopropanol: Max. 200 ppm

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Clopidol

  • Appearance: A white powder
  • Identification: Conformation
  • Loss on drying: Not more than 0.5 %
  • Residue on ignition: Not more than 0.3 %
  • Heavy metals: Not more than 20 ppm
  • Arsenic: Not more than 2 ppm
  • Related material: Not more than 1.0 %
  • Assay (3,5-dichlor-2,6-dimethyl1-4-hydroxypyridine): Not less than 98.0 % and not more than 1-2.0 % (98.0-102.0)

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Diclazuril

  • Characters: Almost white or light yellow powder; practically odorless
  • Identification: UV: absorption max. at 220 nm – 277 nm - IR: conforms to the reference spectrum
  • Related substances (HPLC): total impurities ≤ 2.5 %
  • Loss on drying: ≤ 0.5 % (105°C)
  • Residue on ignition: ≤ 0.1 %
  • Heavy metals: ≤ 20 ppm
  • Assay (HPLC): ≥ 96.0 % (dried substance)

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  • GMP+
  • HACCP
  • ISO 9001
  • ISO 14001
  • EDQM
  • FAMI-QS